This role is a key position in the laboratory of Dr. Brian O'Roak studying the genetic basis of neurodevelopment disorders, such as autism and neural tube defects. In addition, single April 2020, the lab has been leading the SARS-CoV-2 genome sequencing efforts in Oregon. Responsibilities include:
Plans, conducts, and completes laboratory experiments under the supervision of the head of the laboratory. Specific duties will include assistance with mouse colony management and husbandry, tissue dissection, and genotyping. Assists in the culture of induced pluripotent stem cells (iPSCs) and other cell types (mainly neuronal).
Performs primary molecular genetic techniques including PCR, DNA electroporation, gel electrophoresis, Western, Northern, and Southern blotanalysis, protein purification, enzymatic analyses, fluorescent and light microscopy, plasmid preparation, DNA isolation from mouse and human tissues, next-generation library preparation, and studies of gene expression.
Operates a variety of instruments and scientific equipment, including operation, quality control and maintenance.
Assists with experiments and assays, preparing solutions, collecting and entering data, maintaining databases, assuring compliance with established safety procedures and maintaining required documentation.
Collects, records, organizes and verifies the accuracy of data.
Presents experimental results at lab meetings and participates in journal and research group meetings.
Assists in the daily operation of the lab including hazardous waste disposal, sterilization of equipment, cleaning glassware, general servicing of equipment and ordering lab supplies, and preparation of media and buffers.
Bachelor's Degree with major courses in the biological sciences; OR Associates Degree with 3 years experience
Basic laboratory skills
Willingness to work with rodents
High level of attention to detail
Ability to manage time effectively, especially with competing priorities
Ability to communicate well and work with faculty and staff within the department and University
Ability to take initiative and work independently and in a team environment
Ability to complete tasks in an accurate and timely manner
Some schedule flexibility
Bachelors Degree in Neuroscience, Genetics/Genomics, Molecular or Cell Biology
2-4 years of experience serving on a research team
Experience in an academic research setting, especially with qualitative and/or quantitative methods of data collection
Experience with mouse handling and colony management, pluripotent stem cell culture and/or human genetics/genomics
Advanced molecular biology knowledge
Next-generation library preparation experience
Knowledge of standard molecular biology techniques and/or sterile tissue culture technique
Apply here online. Please be sure to upload a cover letter and resume.
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